https://journals.fmsbi.com/JATE <p><strong>Journal of Applied Tissue Engineering</strong> (JATE) " is an international, open access, multi-disciplinary, peer-reviewed journal that provides rapid publication of the most advanced scientific research in basic and applied research on Regenerative Medicine, Tissue Engineering, Cell and tissue-based products, Stem Cells, and Developmental Biology. It ac­cepts Original Papers, Review Articles, Short Communications and Let­ters to the Editor in the fields of Tissue Engineering. The Journal is an official publication of the Iranian Tissue Engineering and Regenerative Medicine Society (ITERMS).</p> <p> </p> <p> </p> Frontier Medical Systems Biology Incorporation en-US The Journal of Applied Tissue Engineering 2383-3149 https://journals.fmsbi.com/JATE/article/view/97 <p><strong>Abstract</strong></p> <p>Purpose: This study aims to assess the impact of adding Bioactive Glass (BG) to Mineral Trioxide Aggregate (MTA) to improve MTA's bioactivity and apatite formation ability. Since BG and MTA share similar bioactivity properties, it is hypothesized that a novel combination of the two mentioned materials could enhance MTA's apatite formation ability and ultimately its bioactivity behavior.</p> <p>Methods: BG-MTA Samples were prepared with concentrations of 10 and 20 wt% BG and submerged in Simulated Body Fluid (SBF) to evaluate their compressive strength. The samples were then characterized using SEM, XRD, and FTIR after 3, 20, and 40 days of incubation.</p> <p>Results: The findings suggest that adding BG to MTA can improve its apatite formation ability and overall bioactivity behavior. This hybrid approach could be a viable option for endodontic clinical application.</p> <p><strong>clinical significance</strong></p> <p>MTA is a material used in dentistry for various procedures, such as root canal therapy and pulp capping. By enhancing the bioactivity of MTA using BG, it can improve its ability to stimulate the formation of new tissue and promote healing, which can lead to better clinical outcomes for patients.</p> Faezeh Mamizad Moghtader Sirus Safaee Yashar Rezaei Mahyar Nesabi Amin Salem Milani Mahdis Nesabi Copyright (c) 2024 The Journal of Applied Tissue Engineering https://creativecommons.org/licenses/by-nc-nd/4.0 2024-04-25 2024-04-25 10 1 10.22034/JATE.2024.97